Hb Murcia (β118(G19)His>Gln): A New Hemoglobin Variant Found in a Spanish Woman

A New Variant of Human Fetal Hemoglobin: Hb Froma.

A Variant of Hemoglobin A2 Found in a Negro Family.

By RALPH C. LKE AND Tii-t s H. J. HuI5MAN T HREE possible variants of Hb-A2 ( a262) with abnormal 6 polypeptide chains have been discovered, namely, Hb-A2’ or Hb-B2 in the Negro race,1’2’4’#{176}”1 Hb-K#{246}ln in one family of German descent13 and Hb-Fbatbush in a family of Puerto Rican ancestry.’4 In this communication, we report the results of studies of an abnormal minor hemoglobin componen...

Rare hemoglobin variant Hb Yaizu observed in Turkey.

OBJECTIVE To determine the characteristic features of the rare hemoglobin (Hb) variant Hb Yaizu to enable laboratory diagnosis of the hemoglobin variants during screening programs. MATERIALS AND METHODS Genomic DNA was obtained from the 4 members of a family living in Denizli province, an Aegean region of Turkey. Blood cell counts, hemoglobin composition, hemoglobin electrophoresis (both alka...

Hb O Padova in a Spanish Family.

Haematological and biochemical aspects of a new family with heterozygous Hb O Padova [alpha 30(B11) Glu----Lys] is described. This variant has been found on a screening programme of abnormal haemoglobin in cord blood. It was separated by cellulose acetate, isoelectric focusing, citrate agar, DEAE-cellulose chromatography and by cation exchange high-performance liquid chromatography. The heat st...

Transient neonatal cyanosis associated with a new Hb F variant: Hb F viseu.

Neonatal cyanosis in healthy newborns can be associated either with methemoglobin due to cytochrome b5 reductase deficiency or to M-hemoglobin, a group of hemoglobin variants resulting from mutations in the globin chain genes. We report the clinical case of a neonate with cyanosis and normal cardiac and respiratory function. At birth the hematological parameters were normal; however, the methem...